Director/Senior Director, Controller at Senti Biosciences
South San Francisco, CA, US
Thank you for your interest in a career at Senti Biosciences. Our mission is to create a new generation of smarter medicines that outmaneuver complex diseases in ways previously inconceivable. We are passionate about designing gene circuits to improve the “intelligence” of cell and gene therapies in order to enhance their therapeutic effectiveness against a broad range of diseases that conventional medicines are unable to address.
At Senti, we find purpose and meaning knowing that our efforts have the potential to improve the lives of patients and their families with more effective and safer treatment options. With science as our foundation and empathy as our key guiding principle, colleagues become friends, managers become mentors, and with time, cancer becomes history.
Senti Biosciences is searching for a full-time Corporate Controller who will manage all aspects of our accounting function. The Corporate  Controller is responsible for overseeing the timeliness, efficiency, and accuracy of the month-end and quarter-end close processes, internal financial reporting to management, as well as the company’s financial statements.  This role will partner across the organization to improve all touch points required to insure an accurate and timely financial close, and to identify and provide solutions for process challenges.  The Controller must possess superior people management skills to develop staff and encourage the team’s growth by providing direction in planning, decision-making and continuous process improvement. This position reports to the CFO.


    • Provide oversight on accounting operations and financial systems
    • Ensure financial results are presented consistently, accurately, and meet all compliance standards including US GAAP
    • Ensure the integrity and accuracy of information provided to the external auditors in relation to the annual audit and quarterly reviews
    • Oversee the company's equity plans, including the stock option and ESPP programs
    • Provide oversight and integration of outsourced functions, including tax
    • Manage other finance-related activities, including general accounting, treasury, and interactions with transfer agent, banks and investment managers
    • Ensure the effectiveness of internal controls and integrity of accounting records and resulting financial statements, working to establish full compliance with all requirements, including SOX
    • Prepare materials and provide updates for executive management in preparation for audit committee / board of director’s meetings
    • Provide cross-functional support to the Company as needs arise, including special projects, system improvements or ad-hoc financial analysis


    • Bachelor’s degree (preferably with accounting and/or business/management focus)
    • CPA license 
    • Experience at a Big Four certified public accounting firm 
    • Previous experience in-house at public biotech company
    • Strong knowledge of U.S. GAAP reporting
    • Strong leadership skills in building a team and focuses on the continuous development and growth of the capabilities and performance of team members
    • Maintains the highest levels of ethics and integrity
    • Strong collaborator with excellent organizational skills
    • Ability to perform at high levels in a fast-paced ever-changing environmentExcellent written and oral communication skills
    • Strong knowledge of SEC rules and regulations, procedures and practices 
    • Functional understanding of ERP systems, Netsuite specific knowledge a plus
Senti Bio is a leading gene circuit company designing gene circuits to create a new generation of “smarter medicines" and enhance the therapeutic effectiveness of cell and gene therapies against a broad range of diseases that are unaddressed by current standards of care. We are proud to count Leaps by Bayer, NEA, 8VC, Matrix Partners China, Mirae Asset Capital, Amgen Ventures, and others among our investors. In December 2021, Senti Bio and Dynamics Special Purpose Corp. (Nasdaq: DYNS), a special purpose acquisition company (SPAC), announced a definitive business combination agreement to create a public company focused on Gene Circuit-engineered cell and gene therapies. The transaction is expected to be completed in the second quarter of 2022. Senti Bio is based in South San Francisco, CA, USA.
We are committed to an inclusive and diverse Senti Bio. We believe that different perspectives lead to better ideas, and better ideas allow us to better understand the needs and interests of our diverse Senti Team. We welcome people of different backgrounds, experiences, abilities and perspectives and are an equal opportunity employer.