Accounting Manager at Senti Biosciences
South San Francisco, CA, US
Thank you for your interest in a career at Senti Biosciences. Our mission is to create a new generation of smarter medicines that outmaneuver complex diseases in ways previously inconceivable. We are passionate about designing gene circuits to improve the “intelligence” of cell and gene therapies in order to enhance their therapeutic effectiveness against a broad range of diseases that conventional medicines are unable to address.
At Senti, we find purpose and meaning knowing that our efforts have the potential to improve the lives of patients and their families with more effective and safer treatment options. With science as our foundation and empathy as our key guiding principle, colleagues become friends, managers become mentors, and with time, cancer becomes history.
Senti Bio is looking to add a hands-on Accounting Manager to our growing team. You will be working closely with the rest of the accounting and finance team to lead many aspects of the financial close and day to day operations.


    • Assist in the monthly close process including Fixed Assets, accruals, pre-paid's and other aspects of the financial close.
    • Prepare journal entries and update bank and account reconciliations.
    • Monthly trend analysis to ensure all expenses are captured and booked according to GAAP.
    • Assist in day-to-day operations of business including ensuring accurate and timely processing of AP invoices.
    • Assist with other accounting function(s), including the review of contracts and payroll processing.
    • Work closely with AP Specialist and other departments to ensure that purchase orders and invoices are booked appropriately and reflect correct GL accounts, project coding etc.
    • Provide support for external financial audits and prepare schedules as needed.
    • Assist with Sales and use tax filing, property tax, Delaware Franchise tax and other business compliances.
    • Assist in developing strong internal control procedures, identifying opportunities to enhance process and controls across all business areas.


    • BS/BA in Accounting or equivalent with a solid knowledge of GAAP, general ledger and financial statements
    • Self-motivated, versatile and enjoy working in a fast-paced environment and managing multiple projects and tasks.
    • 6 year or more years progressive experience required.
    • Excellent written and interpersonal communication skills.
    • Advanced MS Excel and Word skills.
    • Experience with NetSuite, Coupa, Mineral Tree or desired

Salary and Benefits

    • Base pay and stock options to be determined based on application qualifications with the aim of being competitive with similar roles in the area
    • Significant growth opportunity as the company expands
Senti Bio is a leading gene circuit company designing gene circuits to create a new generation of “smarter medicines" and enhance the therapeutic effectiveness of cell and gene therapies against a broad range of diseases that are unaddressed by current standards of care. We are proud to count Leaps by Bayer, NEA, 8VC, Matrix Partners China, Mirae Asset Capital, Amgen Ventures, and others among our investors. In December 2021, Senti Bio and Dynamics Special Purpose Corp. (Nasdaq: DYNS), a special purpose acquisition company (SPAC), announced a definitive business combination agreement to create a public company focused on Gene Circuit-engineered cell and gene therapies. The transaction is expected to be completed in the second quarter of 2022. Senti Bio is based in South San Francisco, CA, USA.
We are committed to an inclusive and diverse Senti Bio. We believe that different perspectives lead to better ideas, and better ideas allow us to better understand the needs and interests of our diverse Senti Team. We welcome people of different backgrounds, experiences, abilities and perspectives and are an equal opportunity employer.