Scientist, Medicinal Chemistry at ORIC Pharmaceuticals
South San Francisco, CA, US

Work as part of an interdisciplinary drug discovery team to design and synthesize novel molecules for evaluation against ORIC’s targets.


  • Effectively design and synthesize drug candidates that advance SAR based on data analysis of biological, DMPK, and physicochemical properties data
  • Work closely with the Medicinal Chemistry department and with the broader project teams to reach project milestones
  • Efficiently execute the synthesis, purification and characterization of small molecules
  • Develop and implement the design of synthetic routes to target compounds
  • Analyze data, interpret results and recommend appropriate action
  • Be a creative problem solver in the face of synthesis and project difficulties
  • Keep abreast of recent scientific developments, patents and primary literature
  • Prepare patent procedures and experimental write-ups, summaries and quantitative analyses
  • Prepare presentation materials and clearly communicate research results at internal and external meetings
  • Maintain a detailed laboratory notebook according to corporate standards and SOPs
  • Participate in keeping the laboratory environment safe and well-organized

Qualifications & Experience:

  • PhD degree in Organic or Medicinal Chemistry with 0-3 years of experience (or a Bachelor with 5-10 years of relevant experience in the pharmaceutical/biotech industry or Masters degree with 3-8 years of extensive industry experience and skills comparable to a PhD)
  • Strong academic and practical background in modern synthetic, organic or medicinal chemistry
  • Experience and scientific understanding of modern drug discovery technologies including, molecular modeling, DMPK, metabolism and physical properties is a plus but not required
  • Demonstrated ability to work in a team environment and to multitask
  • Strong communication skills and work ethic
  • A commitment to continuous learning and a demonstrated ability to perform in a fast-paced environment with rapidly-changing priorities