Scientist, Medicinal Chemistry at ORIC Pharmaceuticals
South San Francisco, CA, US

Work as part of an interdisciplinary drug discovery team to design and synthesize novel molecules for evaluation against ORIC’s targets.

Responsibilities:

  • Effectively design and synthesize drug candidates that advance SAR based on data analysis of biological, DMPK, and physicochemical properties data
  • Work closely with the Medicinal Chemistry department and with the broader project teams to reach project milestones
  • Efficiently execute the synthesis, purification and characterization of small molecules
  • Develop and implement the design of synthetic routes to target compounds
  • Analyze data, interpret results and recommend appropriate action
  • Be a creative problem solver in the face of synthesis and project difficulties
  • Keep abreast of recent scientific developments, patents and primary literature
  • Prepare patent procedures and experimental write-ups, summaries and quantitative analyses
  • Prepare presentation materials and clearly communicate research results at internal and external meetings
  • Maintain a detailed laboratory notebook according to corporate standards and SOPs
  • Participate in keeping the laboratory environment safe and well-organized

Qualifications & Experience:

  • PhD degree in Organic or Medicinal Chemistry with 0-3 years of experience (or a Bachelor with 5-10 years of relevant experience in the pharmaceutical/biotech industry or Masters degree with 3-8 years of extensive industry experience and skills comparable to a PhD)
  • Strong academic and practical background in modern synthetic, organic or medicinal chemistry
  • Experience and scientific understanding of modern drug discovery technologies including, molecular modeling, DMPK, metabolism and physical properties is a plus but not required
  • Demonstrated ability to work in a team environment and to multitask
  • Strong communication skills and work ethic
  • A commitment to continuous learning and a demonstrated ability to perform in a fast-paced environment with rapidly-changing priorities