Bioengineering Research Associate at CellFE
Alameda, CA, US

CellFE is a venture-backed company with a mission to make advanced therapies accessible to all by transforming the way gene therapies are manufactured. The company uses a microfluidics-based cell engineering platform that can be adapted universally to enable low-cost, high-yield manufacturing of gene therapies at scale. CellFE's first generation of products is being developed for contract manufacturers and pharmaceutical companies that specialize in ex-vivo cell therapy and viral vector ("VV") manufacturing.

Our values guide our work: There is a way, Pull together, and Hard work.

 

Position summary: Candidate will be responsible for researching and developing new Cas9 related applications through the use of CellFE's microfluidic platform, as well as work within a team to optimize parameters for Cas9 transfection using the same platform.

The successful research associate in bioengineering will:

  • Perform experimentation and deliver results relating to new Cas9 applications and process optimization of CellFE platform
  • Work within an interdisciplinary team to design and implement robust operating protocols for delivery to customers

This position is based in Alameda, CA and is a member of the CRISPR/Cas9 team, reporting to the project lead.


Specific Responsibilities:

  • Transfect various cell lines and biological payloads - including CRISPR/Cas9, mRNA, and plasmid - using CellFE and competitor platforms
  • Operate microfluidic devices using CellFE patented technology
  • Research, create, and execute on experiments based on goals relayed by team lead
  • Analyze experimental data independently and present results in a clear and critical manner
  • Devise and optimize robust operating protocol for Cas9 RNP based knock-out and knock-in using microfluidic platform for third parties
  • Collaborate with team in order to generate preliminary data for various CRISPR/Cas9 applications

Qualifications:

  • Minimum Bachelor's degree in bioengineering, mechanical engineering, biotechnology, molecular biology, or related field; Master's degree desirable
  • Lab experience (12+ months) in a relevant setting
  • Knowledge of mechanical engineering, biological, biochemical or physics principles
  • Committed to scientific rigor, data integrity, documentation, and traceability
  • Excellent verbal and written communication skills, adaptability and ability to work in a fast-moving and dynamic research environment
  • Experience analyzing and presenting research data to peers, as well as to leadership team
  • Proficient with SharePoint/OneDrive and Microsoft Excel, PowerPoint, Word

Preferred Qualifications:

  • Experience with mammalian cell culture, transfection, and analysis
  • Experience with molecular biology techniques: DNA or RNA extraction, PCR, DNA gels, plasmid cloning, transfection, etc.
  • Experience with cell biology readout: flow cytometry, cell counting, cell phenotyping, microscopy, sequencing, etc.
  • Experience with microfluidic development and testing: operating syringe, peristaltic, and pneumatic pump sources
  • Proficient with software's such as, FlowJo, Prism, or 2D and 3D CAD programs
  • Previous work experience in a biotechnology company or contract research organization is a plus

Competencies:

  • Ability to multi-task in a fast-paced environment
  • Willingness to ask questions and follow instructions
  • Able to grasp scientific principles and learn new techniques quickly
  • Accurately records and processes data in a timely manner
  • Works well independently, as well as in a team environment
  • Effective problem solving and analytical skills; results oriented focus
  • Highly organized
  • Excellent time management and interpersonal skills
  • Patience, decisiveness, and a meticulous approach to tasks
  • Excellent verbal and written communications skills; strong technical writing skills
  • Team player who is willing to be flexible with scheduling and coordinating experiments
  • Reliable, with a professional demeanor

CellFE is an equal opportunity employer