Process Development Engineer at ZymoChem
San Leandro, CA, US

The Opportunity

We are hiring a Process Development Engineer to lead the Process Development & Scale-up (PD&S) Group for the fast-paced, milestone-driven development of the company’s proprietary carbon conserving bioprocesses. This role is a career-defining opportunity to gain diverse experiences with assembling and scaling commercially-relevant bioprocess workflows by exploring a combination of both established and cutting-edge technologies. The Process Development Engineer will also have opportunities for consistent multi-disciplinary collaborations with internal R&D groups as well as the company’s external partners to accelerate the scale-up of fermentation and downstream product recovery processes from the bench top to the pilot and demonstration levels.


  • Design commercially-scalable processes for the recovery and purification of microbial fermentation-based products

  • Lead the hands-up setup, execution, and clean-up of bench-scale downstream processing (DSP) unit operations for both proof-of-concept experiments and benchmarking studies to meet project milestones aimed at achieving product purity and performance at industrial specifications

  • Sampling and sample processing, in addition to establishing new analytical approaches for evaluating process streams

  • Routinely interface with and support the Fermentation Group, and also collaborate with CMO partners on DSP scale-up endeavors

  • Manage expansion of the PD&S Group’s capabilities by exploring new technologies and strategies to improve bio-product recovery & purification and accelerate scale-up efforts

  • Contribute to the development of ZymoChem’s IP strategy & portfolio toward expanding the company’s competitive position

  • Interface with the company’s data management system to record DSP-based data and implement statistical analyses on large data sets

  • Support the maintenance of the company’s product recovery and purification technologies via hands-on equipment troubleshooting & repair


  • PhD or MS in (Bio)chemical Engineering, Chemistry, Process Engineering, Material Science, or a related discipline

  • PhD with 2+ years (or MS degree with 4+ years) of industrial/startup experience working directly with bench and pilot-scale bioprocess development

  • Hands-on expertise with chemical separations equipment and related analytical devices is a requirement

  • Experience with microbiology/fermentations, bioreactors and bioprocess-related unit operations

  • Solid fundamental knowledge of biochemical & process engineering principles including mass balance & transport, reactor design, fluid dynamics, and process control

  • Prior industrial work with modeling software (ASPEN, SuperPro) and/or building computational models; familiarity with scripting tools such as Python and R is a plus

  • Strong aptitude for hands-on work with equipment along with a rigorous attention to details with experimental design, execution, and record keeping

  • Excellent time management skills, effective with multitasking, and an adept ability to improvise work plans while maintaining efficiency

  • Capability and willingness to work extended days, off-peak hours, and weekends

ZymoChem offers full-time employees a competitive base salary and benefits package, and the company is an equal opportunity employer. If this position aligns with your career aspirations, please apply using the form below.