Senior Research Associate, Protein Engineering at Atreca
South San Francisco, CA, US

Atreca is a dynamic biotechnology company applying its Immune Repertoire Capture® (IRC™) technology to discover and develop novel cancer immunotherapeutics. By profiling the clinically relevant, active B cell responses of patients, we are building a portfolio of tumor-targeted antibodies.

We are seeking a motivated and enthusiastic Research Associate or Sr Research Associate to join our Protein Engineering group. The successful candidate will play a key role in further developing our yeast display platform and applying it to optimize and generate differentiated antibody and bispecific therapeutics.

Primary Duties & Responsibilities:

  • Establish yeast cultures and perform flow cytometry assays
  • Sort libraries of antibody variants by FACS and help with NGS sample preparations
  • Develop methods for selecting yeast-displayed antibodies bound to cancer cells
  • Follow laboratory safety guidelines and practices

Requirements:

  • MS in Cell Biology, Molecular Biology, Immunology, Bioengineering, etc., or BS/BA with 2+ years of relevant research experiences (industry experience preferred)
  • Expertise in flow cytometry assays and data analysis (FlowJo preferred)
  • Experience with basic molecular biology techniques (DNA isolation, PCR, etc.)
  • Strong team spirit: capable of working in a team-based, interdisciplinary environment and collaborating with scientists and associates in a fast-paced, energetic environment
  • Exceptional communication, organization, and record keeping
  • Independent and self-motivated, with a strong sense of urgency and ability to drive a project to completion within timelines

Preferred Experience:

  • Experience with yeast display or other display platforms (phage display, mammalian display)
  • Experience with next generation DNA sequencing (including sample preparation, data analysis)
  • Experience with antibody biochemical assays (e.g., ELISA, SPR, BLI)
  • Experience with relevant scientific software (Geneious, GraphPad)
  • Experience with cell-based assays using mammalian cell lines
  • Knowledge of bioinformatics tools and immunology is a plus

Exact title commensurate with experience. Atreca is an equal opportunity employer.