Research Associate - DMPK at Rapt Therapeutics
South San Francisco, CA, US

RAPT Therapeutics, a clinical stage pharmaceutical company developing small molecule agents to target immune drivers of cancer and inflammation, is seeking a highly motivated and energetic DMPK team member.    

POSITION SUMMARY 

DMPK 

The selected candidate will conduct the lab-based evaluation of ADME/PK properties of proprietary compounds, by developing and performing in vitro ADME assays and quantitative analysis, playing an active part in our drug discovery and development efforts. 

ESSENTIAL FUNCTIONS 

Conduct in vitro ADME assays, such as metabolic stability, P450 inhibition, solubility and plasma protein binding 

Develop new assays as required 

Help with formulation preparation as needed 

Perform biological sample preparation and LC/MS-based quantitative analysis to support studies with discovery and development candidates  

Collect, analyze, summarize, upload to internal databases and report high quality data in a timely manner 

Identify, troubleshoot and communicate on issues arising while performing regular duties 

Participate in maintaining laboratory equipment and actively engage in safe and efficient of laboratory operations 

Collaborate with team members from multiple functional areas  

Participate in project and PK team meetings.