RAPT Therapeutics, a clinical stage pharmaceutical company developing small molecule agents to target immune drivers of cancer and inflammation, is seeking a highly motivated and energetic DMPK team member.
The selected candidate will conduct the lab-based evaluation of ADME/PK properties of proprietary compounds, by developing and performing in vitro ADME assays and quantitative analysis, playing an active part in our drug discovery and development efforts.
Conduct in vitro ADME assays, such as metabolic stability, P450 inhibition, solubility and plasma protein binding
Develop new assays as required
Help with formulation preparation as needed
Perform biological sample preparation and LC/MS-based quantitative analysis to support studies with discovery and development candidates
Collect, analyze, summarize, upload to internal databases and report high quality data in a timely manner
Identify, troubleshoot and communicate on issues arising while performing regular duties
Participate in maintaining laboratory equipment and actively engage in safe and efficient of laboratory operations
Collaborate with team members from multiple functional areas
Participate in project and PK team meetings.