Associate Scientist, Compound Manager at Notable Labs
Foster City, CA, US
Are you a seasoned compound management professional looking for a mission driven company where the work you do will directly impact human lives?
Notable Labs seeks an Associate Scientist of Compound Management to own the compound management function from compound preparation to SOP documentation to managing our QC process. This role is an ideal opportunity for individuals who thrive in a changing environment and enjoy supporting and delivering world-class products that meet both external and internal customer needs. As our resident compound expert, you will have the opportunity to own your system- while helping change the way that cancer is treated. You will enjoy both the challenge of building new processes, and the rigor and accountability of making and delivering high quality products for Notable Labs. And as we continue to grow, you will have the opportunity to work with our awesome engineering and science teams to move towards an increasingly automated compound management system.
This is both a strategic and a tactical position, with a significant bench research component.
What You Will Do:
Carry out compound making processes such as the creation of reagents, antibodies, and enzymes, in an automated clinical and research laboratory
Operate production equipment and monitor process parameters including temperature, pressure, pH and agitation speed in order to produce buffers and media according to specification.
Assist in the receiving, handling, and monitoring of quantities of raw materials and finished products
Develop quality control tests for reagent qualification and stability testing
Maintain thorough, accurate and detailed documentation in batch records of all work produced
Document manufacturing activities and quality control results and deviations
Identify and help implement process changes to streamline throughput of reagent manufacturing, including the introduction of process automation and identifying LIMS requirements
Partner with R&D and production scientists to troubleshoot and problem solve processing issues, provide custom materials for customer evaluation and/or identify process improvement opportunities within the plant to improve efficiencies and/or processes.
Create SOPs for all manufacturing related processes, and act as subject matter expert for revisions or improvements to manufacturing documents
Work closely with both R&D and production teams to create a shared core resource
Who You Are:
BS in Chemistry or AAS degree in Process Technology (or equivalent) and a minimum of 4 years as a Reagent Manufacturing Supervisor in a relevant field. More than 5 years of experience as a Reagent Manufacturing Supervisor in a relevant field will be considered in lieu of degree.
2+ years of QC testing
The ability to be cross-trained to perform other job duties as needed
Proficiency with concentration calculations and dilution measurements related to safe handling of materials and maintaining an overall priority on safety within a production environment.
Attention to detail and the ability to develop and follow written procedures
Adaptability to changes in a fast-paced environment
Familiarity with automated instrumentation (Hamilton Liquid Handler and Echo acoustic liquid handler) is a plus.
Familiarity with software inventory systems and basic computer skills: Google Docs, Mac
What we can offer you:
The opportunity to directly fight cancer, one patient at a time
Exposure to experts from diverse backgrounds ranging from engineering, data science, operations, clinical medicine, patient advocacy, and beyond
Work in a collaborative environment with a team dedicated to both personal and scientific growth and development
Highly competitive, early stage company compensation package, with incredible growth opportunities
Outstanding healthcare benefits
Flexible vacation policy
… did we mention daily catered lunch?
More about us:
Notable Labs is a precision medicine company that has a translational drug discovery platform focused on identifying therapeutic options for relapsed and refractory cancer patients.
Our clinical research lab helps oncologists identify personalized combinations of existing FDA-approved treatments for patients. We’ve developed a high throughput robotic flow cytometry lab platform that screens thousands of FDA-approved drug combinations against the patient’s own cancer cells to help predict safer and more effective cancer treatments. Our lab has completed initial feasibility studies with clinicians in relapsed Acute Myeloid Leukemia & Myelodysplastic Syndrome, with an 84% predictive rate. Focusing on individual patients and existing treatments, we’re working to discover novel uses of drugs and defining mechanisms underlying cancer progression and drug resistance.
Our research and development platform extends our clinical research to drug discovery, testing novel compounds with primary patient samples for pharmaceutical and biotechnology companies. Using our automated, high-throughput, multi-parametric drug screening research platform, industry partners can assay the biological impact of novel compounds on primary cells in a physiologically relevant environment. This helps our partners stratify patients by their predicted responsiveness, increasing the probability of successful clinical development. We are actively partnering with pharmaceutical companies that have preclinical and clinical stage drug pipelines in Acute Myeloid Leukemia, Myelodysplastic Syndrome, or related hematological malignancies to profile experimental drug activity in patient samples.
Our investors include Builders Venture Capital, Founders Fund, First Round Capital, Y Combinator, several prominent angels and seed-stage funds, and Accelerate Brain Cancer Cure, a venture philanthropy firm founded by Steve Case. We have offices and a laboratory in San Francisco’s SoMa district.
At Notable Labs we value diversity and are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.