Sr Research Associate, In Vivo Pharmacology (Temp) at Atreca
Redwood City, CA, US
The Research Associate (RA) will work assisting the in vivo preclinical studies in Atreca’s oncology research program. In this role, the RA will perform multiple efficacy studies testing various therapeutic agents and combination regimens in mouse tumor models. Here the RA will rely on their expertise to initiate and measure tumor progression, administer therapeutics, and measure their effects on tumor growth. The successful candidate will have the opportunity to interact and collaborate with a multidisciplinary team in a dynamic scientific environment. Job title/compensation commensurate with experience and qualifications.

Duties and Responsibilities:

Perform in vivo studies to evaluate anti-cancer efficacy of test agents in tumor mouse models

Monitor mice groups enrolled in drug efficacy and mechanism of action studies

Perform drug dosing by various routes of administration

Monitor in-life study measurements: tumor volume, body weight, tracking overall health condition and survival of mice

Entering data in animal management software

Availability to work on weekends (rotating schedule)

Follow laboratory safety guidelines and practices

Required Experience:

BS in Biology or related field with 5+ years of direct experience with mouse syngeneic and/or xenograft tumor models in a commercial vivarium

Absolutely Required: Demonstrated experience with subcutaneous tumor models. And ability to work independently, to perform multiple mouse studies simultaneously and to report study data

Experience with orthotopic tumor models is desirable (models of renal cell carcinoma, colorectal cancer and mammary carcinoma)

Experience with tasks related to efficacy studies: tumor cell implantation, tumor volume measurement, blood draws (survival and terminal bleed), necropsy and tissue collection and processing

Experience with dosing of therapeutic agents by various routes of administration (IP, oral gavage and IV)

Excellent organizational skills and ability to collaborate with Atreca’s scientific team

Proficiency in animal welfare and overall knowledge of federal guidelines for animal care and use