Sr. RA - Target Biochemistry at Atreca
Redwood City, CA, US
Atreca is a biotechnology company focused on applying its Immune Repertoire Capture™ technology to discover and develop novel cancer immunotherapeutics. Located in Redwood City, California, Atreca is looking for talented, entrepreneurial people who are dedicated to making a positive impact on human health. We have a unique opportunity for a highly motivated individual to become a key member of a growing biotechnology company.
In this position, the successful candidate will apply her/his skills and expertise in protein biochemistry to assist in purifying protein targets bound by Atreca antibodies so that they may be identified using protein sequencing techniques. These methods include immunoprecipitation, chromatography and other protein biochemistry techniques.
PRIMARY DUTIES & RESPONSIBILITIES
Assist with antibody target identification efforts
Perform pilot and preparative immunoprecipitations on cell and tumor extracts
Purify proteins and other macromolecules using chromatographic methods
Generate lysates and subcellular fractions from tissue culture cells (including radiolabeled cells) and mouse tumors
Characterize purified material by 1D & 2D western blots, autoradiography
Work with other project team members and communicate results with the team
Follow laboratory safety guidelines and practices
Bachelor’s degree in molecular biology, biochemistry or related discipline
REQUIRED: 1-6 years research experience performing protein purification and/or immunoprecipitation
Extensive experience with immunoblots, including slot and western blots
Experience with SDS-PAGE and electrophoretic transfer of proteins to membranes
Must have excellent trouble shooting, organization, and planning skills, and the ability to work under timeline in a fast-paced environment.
Excellent written and oral communication skills.