Research Associate - Senior Research Associate, In Vivo Pharmacology – Discovery Biology at Nurix
San Francisco, CA, US
We are seeking a highly skilled and motivated Research Associate/Senior Research Associate to support Nurix’s mission of targeting E3 ubiquitin ligases in the areas of oncology and immunology. The ideal candidate will have expertise in small molecule PK/PD and efficacy studies in oncology or immuno-oncology.
This individual will work closely with our drug discovery project scientists on late-stage lead optimization of novel compounds to support dose and schedule optimization, execution of pharmacodynamic biomarker assays, in vivo efficacy, and characterization of ex vivo immune cell function. The candidate must be self-driven, organized, able to work well with project scientists, and able to thrive in an exciting environment in a rapidly-growing company.
B.S. in immunology, cancer biology or related field with 1-2+ years (RA) or 8+ years of industry experience (SRA)
In vivo pharmacology expertise with xenograft or syngeneic tumor models required
Experience with formulating and dosing of small molecules and rodent PK/PD studies preferred
Excellent hands-on in vivo skills: IV, PO dosing, tumor implantation, blood/tissue collection, etc.
Experience in flow cytometry desired
Excellent communication and presentation skills
Excellent interpersonal skills and ability to work productively in a highly dynamic environment
Fit with Nurix Culture and Values
Team orientation; highly collaborative; solutions and results-oriented focus
Strong scientific curiosity and initiative; hands-on and resourceful
Self-driven and enthusiastic with the ability to thrive in a dynamic environment