SCIENTIST - Microbiome Sciences at Siolta Therapeutics
San Francisco, CA, US
Siolta Therapeutics is seeking highly motivated and talented technical staff scientists to provide
support for the company’s therapeutic development program focused on prevention/treatment of
airway inflammation through manipulation of the gut microbiome. The successful candidate will
work closely with other team members on preclinical studies of a rationally designed mixedspecies
therapeutic microbial consortium. The successful candidate will be technically proficient
in microbial culture, molecular techniques and experienced in animal handling.

Essential Qualifications:
Ph.D. in microbiology, microbial genomics, microbial ecology, microbial bioinformatics
or other related scientific field
Experience with next generation sequencing and analysis
Demonstrated aptitude in biostatistics, analysis of high-dimensional biological and
genomic data sets, and the application of such methods to interrogate biological systems
Proficiency in UNIX/Linux development environment with knowledge in at least one
analytical language (e.g. R or Matlab)
Must be capable of applying new knowledge and skills creatively while working both
independently and collaboratively in fast paced development environment
Strong publication record

Preferred Qualifications:

Experience with humanized germ-free mice
Working knowledge of mammalian immunology
Participation in IND enabling studies
Key Responsibilities:
Generate, analyze and interpret microbiota, metagenomic and metabolomic data sets to
identify microbial and functional ecology correlates associated with inflammation
Develop quantitative methods, metrics, and analytical procedures for evaluating and
interpreting microbiome datasets as they relate to associated immunological responses of
Maintain current awareness of microbiome literature, emerging approaches and methods
in microbiome genomic and systems biology analyses
Contribute to the development of Siolta’s intellectual property estate

Who we are:

Siolta Therapeutics is an early-stage biotech located in the San Francisco Bay Area focused on
developing microbial therapeutics to treat or prevent inflammatory disease. We are developing a
strong multi-disciplinary team of scientists to support our vision of rationally designed microbial
therapeutic development.

Siolta Therapeutics offers competitive salary, equity plans, and full benefit packages that are
commensurate with experience.

To Apply:
Please provide a cover letter, CV, and three references