CLIA Laboratory Director at Notable Labs
San Francisco, CA, US
Changing the way cancer is treated is our personal mission, which starts with putting patients first. We’ve developed an individualized laboratory testing service for cancer patients and their doctors. We screen thousands of FDA-approved drugs against the patients own cancer cells to identify drug combinations that can be immediately prescribed by their doctor without a clinical trial. By repositioning treatment as a patient-centered service we can unlock the power of modern data science and laboratory automation to achieve the promise of combination therapy and personalized medicine.

Our investors include Founders Fund, First Round Capital, Y Combinator, several prominent angels and seed-stage funds, and Accelerate Brain Cancer Cure, a venture philanthropy firm founded by Steve Case. We have offices and a laboratory in San Francisco’s SoMa district.


We’ve developed a high throughput robotic testing platform that uses a patient’s live tumor cells to predict the safest and most effective treatment combinations. We employ an ex vivo assay to survey thousands of drug combination options. To ensure our translational system is predictive we’ve created a proprietary method to mimic the microenvironment of the human body. Our drug panel includes all approved chemotherapies and targeted agents, as well as generic non-oncology drugs that have published anti-neoplastic evidence.

We prioritize the safest combinations from our viability assay by estimating a therapeutic index. Successful hits are counter-screened against normal human cells to determine a customized, relative drug scoring system for each patient. The end result of our process is a CLIA certified report which prioritizes therapeutic options that could be used by the physician and patient.

Position Overview:

We're looking for an experienced, licensed CLIA Laboratory Director to run our CLIA Laboratory. The individual would report to the founders, but interface directly with the Research and Development as well as Engineering teams.


Responsible for the overall CLIA laboratory development and execution in accordance with state and federal guidelines
Recruit, train, and lead testing personnel, ensuring that all employees are adequately qualified and motivated to perform their duties
Lead development, maintenance, and improvement of quality systems
Performing, reviewing, and documenting laboratory quality control procedures and training
Ensure laboratory conditions adhere to safety and environmental requirements
Assist with improvement of the existing test, development of second generation assays, and preparing new tests for CLIA inspections
Maintain and improve standard operating procedures to ensure compliance with all state and federal regulations


Compassion for cancer patients and passion for reinventing cancer treatment
M.D. degree with Board Certification in Pathology or +2 years of high complexity clinical laboratory experience, preferably in the field of clinical chemistry, hematology, cytology, cell-based assays, or other equivalent clinical laboratory testing areas
Currently hold Laboratory Director qualifications specified in CLIA regulations
Experience hosting CLIA inspections and knowledge of regulatory requirements
Experience leading, growing, and scaling clinical laboratories
Ability to work independently with a multi-disciplinary engineering team in a resourceful startup